https://www.crsguidelines.org/index.php?action=history&feed=atom&title=ROCURONIUM_%28ZEMURON%29 2026-04-20T16:50:55Z Revision history for this page on the wiki MediaWiki 1.37.2 https://www.crsguidelines.org/index.php?title=ROCURONIUM_(ZEMURON)&diff=122&oldid=prev 2022-04-04T03:54:58Z

<p>Created page with &quot;&#039;&#039;&#039;Class&#039;&#039;&#039; Skeletal muscle relaxant, neuromuscular blocking agent &#039;&#039;&#039;Pharmacology and Actions&#039;&#039;&#039; # Non-depolarizing neuromuscular blocking agent with intermediate to rapid onset # Acts by competitive inhibition of cholinergic receptors at the motor end-plate # Higher doses produce a longer duration of action &#039;&#039;&#039;Indications for Use:&#039;&#039;&#039; # Facilitate endotracheal intubation # Provide skeletal muscle relaxation for mechanical ventilation &#039;&#039;&#039;Contraindications&#039;&#039;&#039; # Kno...&quot;</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Class&#039;&#039;&#039;<br /> <br /> Skeletal muscle relaxant, neuromuscular blocking agent<br /> <br /> &#039;&#039;&#039;Pharmacology and Actions&#039;&#039;&#039;<br /> <br /> # Non-depolarizing neuromuscular blocking agent with intermediate to rapid onset<br /> # Acts by competitive inhibition of cholinergic receptors at the motor end-plate<br /> # Higher doses produce a longer duration of action<br /> <br /> &#039;&#039;&#039;Indications for Use:&#039;&#039;&#039;<br /> <br /> # Facilitate endotracheal intubation<br /> # Provide skeletal muscle relaxation for mechanical ventilation<br /> <br /> &#039;&#039;&#039;Contraindications&#039;&#039;&#039;<br /> <br /> # Known hypersensitivity to rocuronium<br /> # Myasthenia gravis<br /> <br /> &#039;&#039;&#039;Precautions&#039;&#039;&#039;<br /> <br /> # Severe liver disease.<br /> # Vancomycin and tetracycline antibiotics prolong the effects.<br /> # Tegretol and Dilantin decrease the effects and duration.<br /> <br /> &#039;&#039;&#039;Side Effects:&#039;&#039;&#039;<br /> <br /> # Cardiovascular: arrhythmias, tachycardia<br /> # Respiratory:  bronchospasm, hiccups<br /> # Dermatologic:  rash, itching, injection site edema<br /> # Gastrointestinal:  nausea, vomiting<br /> <br /> &#039;&#039;&#039;Administration:&#039;&#039;&#039;<br /> <br /> # Rapid Sequence Intubation Dose: 1 mg/kg IV/IO, may repeat one time after 2 minutes if   inadequate response is obtained.<br /> <br /> &#039;&#039;&#039;Side Effects and Special Notes:&#039;&#039;&#039;<br /> <br /> # Duration of effect is slightly increased in patients &gt; 65 year<br /> # Compatible with all IV solutions</div>

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