Cgabryszek: Created page with "'''Class''' Vasodilator '''Pharmacology and Actions''' # Cardiovascular effects include: ## Reduced venous tone, causes blood pooling in peripheral veins, decreasing venous return to the heart. ## Decreased peripheral resistance ## Dilatation of coronary arteries (if not already at maximum) and relief of coronary artery spasm. # Generalized smooth muscle relaxation '''Indications''' # Angina # Chest, arm, or neck pain caused by coronary ischemia # Patients with 12-l..."

2022-04-04T03:51:43Z

Created page with "'''Class''' Vasodilator '''Pharmacology and Actions''' # Cardiovascular effects include: ## Reduced venous tone, causes blood pooling in peripheral veins, decreasing venous return to the heart. ## Decreased peripheral resistance ## Dilatation of coronary arteries (if not already at maximum) and relief of coronary artery spasm. # Generalized smooth muscle relaxation '''Indications''' # Angina # Chest, arm, or neck pain caused by coronary ischemia # Patients with 12-l..."

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'''Class'''

Vasodilator

'''Pharmacology and Actions'''

# Cardiovascular effects include:
## Reduced venous tone, causes blood pooling in peripheral veins, decreasing venous return to the heart.
## Decreased peripheral resistance
## Dilatation of coronary arteries (if not already at maximum) and relief of coronary artery spasm.
# Generalized smooth muscle relaxation

'''Indications'''

# Angina
# Chest, arm, or neck pain caused by coronary ischemia
# Patients with 12-lead evidence of acute MI, with / without chest pain
# Cardiogenic pulmonary edema: to increase venous pooling, lowering cardiac preload and afterload.

'''Contraindications'''

# Children younger than 12 years of age.
# Patients currently using Viagra or similar drugs (male or female).

'''Precautions'''

# Generalized vasodilitation may cause profound hypotension and reflex tachycardia.
# Use with extreme caution in hypotensive patients.
# Use with caution in patients with EKG evidence of a right ventricular infarct.

'''Administration'''

# Oral: 0.4 mg tablet / spray sublingually, may repeat every 3-5 minutes as needed for effect.

'''Side Effects and Special Notes'''

# Common side effects include throbbing headache, flushing, dizziness, and burning under the tongue (if given orally), these side effects may be used to check potency.
# Less common: orthostatic hypotension, sometimes marked.
# NOTE: Therapeutic effect is enhanced, but adverse effects are increased when patient is upright.
# Because nitroglycerin causes generalized smooth muscle relaxation, it may be effective in relieving chest pain caused by esophageal spasm.
# May be effective even in patients using paste, discs, or oral long-acting nitrate preparation.
# Patients taking Viagra or similar drugs should not be given nitroglycerin.

NITROGLYCERIN - Revision history