https://www.crsguidelines.org/index.php?action=history&feed=atom&title=MAGNESIUM_SULFATE 2026-04-20T15:27:58Z Revision history for this page on the wiki MediaWiki 1.37.2 https://www.crsguidelines.org/index.php?title=MAGNESIUM_SULFATE&diff=117&oldid=prev 2022-04-04T03:46:15Z

<p>Created page with &quot;&#039;&#039;&#039;Class&#039;&#039;&#039; Anticonvulsant / Antiarrhythmic &#039;&#039;&#039;Pharmacology and Actions&#039;&#039;&#039; # Cardiac: stabilizes potassium pump, correcting repolarization. Shortens the QT interval in the presence of ventricular arrhythmias due to drug toxicity or electrolyte imbalance. # Obstetrics: controls seizures by blocking neuromuscular transmission. Also lowers blood pressure and decreases cerebral vasospasm. &#039;&#039;&#039;Indications&#039;&#039;&#039; # Cardiac: ## Recommended for use in cardiac arrest only if tors...&quot;</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Class&#039;&#039;&#039;<br /> <br /> Anticonvulsant / Antiarrhythmic<br /> <br /> &#039;&#039;&#039;Pharmacology and Actions&#039;&#039;&#039;<br /> <br /> # Cardiac: stabilizes potassium pump, correcting repolarization. Shortens the QT interval in the presence of ventricular arrhythmias due to drug toxicity or electrolyte imbalance.<br /> # Obstetrics: controls seizures by blocking neuromuscular transmission. Also lowers blood pressure and decreases cerebral vasospasm.<br /> <br /> &#039;&#039;&#039;Indications&#039;&#039;&#039;<br /> <br /> # Cardiac:<br /> ## Recommended for use in cardiac arrest only if torsades de pointes or suspected hypomagnesemia is present.<br /> ## Refractory VF (after lidocaine).<br /> ## Torsades de pointes with a pulse<br /> # Obstetrics: Pregnancy &gt;20 weeks with signs and symptoms of pre-eclampsia, defined as:<br /> ## Blood pressure &gt; 180 mm systolic or &gt; 120 mm diastolic with altered mental status, or,<br /> ## Seizures<br /> <br /> &#039;&#039;&#039;Precautions&#039;&#039;&#039;<br /> <br /> # AV block<br /> # Decrease in respiratory or cardiac function<br /> # Use with caution in patients taking digitalis<br /> <br /> &#039;&#039;&#039;Administration&#039;&#039;&#039;<br /> <br /> # Torsades de pointes (not in cardiac arrest): Loading dose of 1 gram infused slowly over 60 minutes.<br /> # In pre-eclampsia/eclampsia patients, 2 grams diluted in 100 mL of normal saline over 5-20 minutes.  May repeat to a total dose of 6 grams.<br /> <br /> &#039;&#039;&#039;Side Effects and Special Notes&#039;&#039;&#039;<br /> <br /> # Principle side effect is respiratory depression.  Ventilatory assistance may be needed.<br /> # Not for pediatric use.<br /> # Magnesium sulfate is very irritating when administered IV, thus dilution is always recommended.</div>

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