https://www.crsguidelines.org/index.php?action=history&feed=atom&title=KETAMINE 2026-04-20T15:28:51Z Revision history for this page on the wiki MediaWiki 1.37.2 https://www.crsguidelines.org/index.php?title=KETAMINE&diff=115&oldid=prev 2022-04-04T03:41:40Z

<p>Created page with &quot;&#039;&#039;&#039;Class&#039;&#039;&#039; A rapid-acting general anesthetic, normal pharyngeal-laryngeal reflexes, normal or slightly enhanced skeletal muscle tone, cardiovascular and respiratory stimulation, and occasionally a transient and minimal respiratory depression. &#039;&#039;&#039;Pharmacology and Actions&#039;&#039;&#039; # Produces an anesthetic state characterized by profound analgesia # Normal or  slightly enhanced skeletal muscle tone # Cardiovascular and respiratory stimulation # Occasionally a transient and m...&quot;</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Class&#039;&#039;&#039;<br /> <br /> A rapid-acting general anesthetic, normal pharyngeal-laryngeal reflexes, normal or slightly enhanced skeletal muscle tone, cardiovascular and respiratory stimulation, and occasionally a transient and minimal respiratory depression.<br /> <br /> &#039;&#039;&#039;Pharmacology and Actions&#039;&#039;&#039;<br /> <br /> # Produces an anesthetic state characterized by profound analgesia<br /> # Normal or  slightly enhanced skeletal muscle tone<br /> # Cardiovascular and respiratory stimulation<br /> # Occasionally a transient and minimal respiratory depression.<br /> <br /> &#039;&#039;&#039;Indications&#039;&#039;&#039;<br /> <br /> # Adult patient with signs of excited delirium where the safety of patient and/or providers is of substantial concern.<br /> <br /> &#039;&#039;&#039;Contraindications&#039;&#039;&#039;<br /> <br /> # Relatively contraindicated in penetrating eye trauma<br /> # Relative contraindication in patients with known cardiovascular disease. (ketamine causes tachycardia<br /> <br /> &#039;&#039;&#039;Administration&#039;&#039;&#039;<br /> <br /> # Administer 1mg/kg IV/IO or 4mg/kg IM.<br /> # May administer a second dose after 5 minutes if the patient is not adequately sedated, only after consult with &#039;&#039;&#039;MEDICAL CONTROL&#039;&#039;&#039;<br /> ## For any signs of emergence phenomena, such as hallucinations, delirium, or increasing agitation, contact &#039;&#039;&#039;MEDICAL CONTROL&#039;&#039;&#039; for discussion of supplemental Versed.<br /> # If post-Ketamine sedation is necessary, contact &#039;&#039;&#039;MEDICAL CONTROL&#039;&#039;&#039; for discussion of supplemental Versed.<br /> <br /> &#039;&#039;&#039;Side Effects and Special Notes&#039;&#039;&#039;<br /> <br /> # Laryngospasm:  this very rare adverse reaction presents with stridor and respiratory distress.  After every administration of ketamine:<br /> ## Prepare to provide respiratory support including bag-valve-mask ventilation and suction, which are generally sufficient in rare cases of laryngospasm.<br /> ## Institute cardiac monitoring, pulse oximetry and continuous waveform capnography<br /> ## Establish IV or IO access, check blood glucose<br /> ## Establish and maintain physical restraint.<br /> # Emergence Reaction:  presents as anxiety, agitation, apparent hallucinations or nightmares as ketamine is wearing off. For severe reactions, consider benzodiazepine.<br /> # Nausea and Vomiting: always have suction available after ketamine administration. Give antiemetic as needed.<br /> # Hypersalivation: Suction usually sufficient.</div>

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