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	<id>https://www.crsguidelines.org/index.php?action=history&amp;feed=atom&amp;title=FENTANYL_%28SUBLIMAZE%29</id>
	<title>FENTANYL (SUBLIMAZE) - Revision history</title>
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	<updated>2026-04-20T15:32:30Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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		<id>https://www.crsguidelines.org/index.php?title=FENTANYL_(SUBLIMAZE)&amp;diff=113&amp;oldid=prev</id>
		<title>Cgabryszek: Created page with &quot;&#039;&#039;&#039;Class&#039;&#039;&#039;  Narcotic analgesic  &#039;&#039;&#039;Pharmacology and Actions&#039;&#039;&#039;  # Potent synthetic narcotic analgesic with actions similar to those of morphine, but action is more prompt and less prolonged # The emetic effect is less than morphine.  &#039;&#039;&#039;Indications&#039;&#039;&#039;  # Adult and pediatric pain management # Chest pain # STEMI  &#039;&#039;&#039;Precautions&#039;&#039;&#039;  # Contraindicated in patients taking MOA inhibitors # Myasthenia gravis # Use with caution with head injuries, ICP, elderly, COPD, liver and k...&quot;</title>
		<link rel="alternate" type="text/html" href="https://www.crsguidelines.org/index.php?title=FENTANYL_(SUBLIMAZE)&amp;diff=113&amp;oldid=prev"/>
		<updated>2022-04-04T03:37:08Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;&amp;#039;&amp;#039;&amp;#039;Class&amp;#039;&amp;#039;&amp;#039;  Narcotic analgesic  &amp;#039;&amp;#039;&amp;#039;Pharmacology and Actions&amp;#039;&amp;#039;&amp;#039;  # Potent synthetic narcotic analgesic with actions similar to those of morphine, but action is more prompt and less prolonged # The emetic effect is less than morphine.  &amp;#039;&amp;#039;&amp;#039;Indications&amp;#039;&amp;#039;&amp;#039;  # Adult and pediatric pain management # Chest pain # STEMI  &amp;#039;&amp;#039;&amp;#039;Precautions&amp;#039;&amp;#039;&amp;#039;  # Contraindicated in patients taking MOA inhibitors # Myasthenia gravis # Use with caution with head injuries, ICP, elderly, COPD, liver and k...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Class&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
&lt;br /&gt;
Narcotic analgesic&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Pharmacology and Actions&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
&lt;br /&gt;
# Potent synthetic narcotic analgesic with actions similar to those of morphine, but action is more prompt and less prolonged&lt;br /&gt;
# The emetic effect is less than morphine.&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Indications&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
&lt;br /&gt;
# Adult and pediatric pain management&lt;br /&gt;
# Chest pain&lt;br /&gt;
# STEMI&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Precautions&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
&lt;br /&gt;
# Contraindicated in patients taking MOA inhibitors&lt;br /&gt;
# Myasthenia gravis&lt;br /&gt;
# Use with caution with head injuries, ICP, elderly, COPD, liver and kidney dysfunction, and bradydysrhythmias.&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Administration&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
&lt;br /&gt;
# Adult Pain Management&lt;br /&gt;
## For patients 6-75 years old: Administer &amp;#039;&amp;#039;&amp;#039;fentanyl (Sublimaze)&amp;#039;&amp;#039;&amp;#039; 0.5-1 mcg/kg INTRANASAL/INTRAMUSCULAR or mixed in 5 mL normal saline and given IV/IO push over 2-4 minutes to a maximum single dose of 100 mcg IV/IO. Reassess patient vital signs and pain scale after 5 minutes.&lt;br /&gt;
## For patients &amp;gt; 75 years old: Administer &amp;#039;&amp;#039;&amp;#039;fentanyl (Sublimaze)&amp;#039;&amp;#039;&amp;#039; 0.5 mcg/kg INTRANASAL/INTRAMUSCULAR or mixed in 5 mL normal saline and given IV/IO push over 2-4 minutes to a maximum single dose of 100 mcg IV/IO. Reassess patient vital signs and pain scale after 5 minutes.&lt;br /&gt;
# Reassess pain scale and vital signs including pulse oximetry every 5 minutes&lt;br /&gt;
# If sufficient pain relief is not obtained with the initial dose, then an additional dose of &amp;#039;&amp;#039;&amp;#039;fentanyl (Sublimaze)&amp;#039;&amp;#039;&amp;#039; 0.5 mcg/kg may be administered IV/IO, IN, IM, provided systolic BP remains above 100 mm Hg for a total max dose of 150 mcg&lt;br /&gt;
# Pediatric Pain Management&lt;br /&gt;
## 1 mcg/kg mixed in 5 mL normal saline and given IV/IO push over 2-4 minutes to a maximum single dose of 100 mcg IV/IO. Reassess patient vital signs and pain scale after 5 minutes.&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Side Effects and Special Notes&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
&lt;br /&gt;
# Sedation, euphoria, dizziness, and diaphoresis.&lt;br /&gt;
# Seizures with high doses.&lt;br /&gt;
# Nausea and vomiting.&lt;br /&gt;
# Bronchoconstriction, respiratory depression or arrest if given as a rapid IV infusion.&lt;br /&gt;
# Can be reversed with Narcan.&lt;/div&gt;</summary>
		<author><name>Cgabryszek</name></author>
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