Cgabryszek: Created page with "'''Class''' Platelet inhibitor/Anti-inflammatory '''Pharmacology and Actions''' # ASA inhibits blood clotting. It inhibits the formation of thromboxane A2, a platelet aggregating, vasoconstricting prostaglandin. ASA in low doses, however, inhibits the production of thromboxane A2 in the platelet more than it does the production of prostacyclin in the endothelial cells. # Platelet aggregation has been implicated in the pathogenesis of atherosclerosis contributing to th..."

2022-04-04T03:19:57Z

Created page with "'''Class''' Platelet inhibitor/Anti-inflammatory '''Pharmacology and Actions''' # ASA inhibits blood clotting. It inhibits the formation of thromboxane A2, a platelet aggregating, vasoconstricting prostaglandin. ASA in low doses, however, inhibits the production of thromboxane A2 in the platelet more than it does the production of prostacyclin in the endothelial cells. # Platelet aggregation has been implicated in the pathogenesis of atherosclerosis contributing to th..."

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'''Class'''

Platelet inhibitor/Anti-inflammatory

'''Pharmacology and Actions'''

# ASA inhibits blood clotting. It inhibits the formation of thromboxane A2, a platelet aggregating, vasoconstricting prostaglandin. ASA in low doses, however, inhibits the production of thromboxane A2 in the platelet more than it does the production of prostacyclin in the endothelial cells.
# Platelet aggregation has been implicated in the pathogenesis of atherosclerosis contributing to the acute episodes of TIA's, unstable angina, and acute myocardial infarction.
# Unstable angina is precipitated by a sudden fall in coronary blood flow. One possible mechanism is platelet aggregation.
# ASA has been shown to be beneficial in decreasing sudden cardiac death and myocardial infarction in patients with unstable angina.
# ASA has been shown to be of added benefit in maintaining vessel patency after thrombolytic therapy.

'''Indications'''

# Patients with chest pain or other symptoms, which may be of cardiac origin.
# ASA is not to be used for analgesia (i.e. headache).

'''Contraindications'''

# Children under 12 years of age
# Known hypersensitivity to drug, especially allergy induced asthma
# Current ulcer or GI bleed

'''Administration'''

# Chew four 81 mg ASA chewable tablets (324 milligrams total) if the patient is able to swallow voluntarily.

'''Side Effects and Special Notes'''

# ASA is one of the few interventions that has been shown to improve mortality and therefore should be considered early in the care of the patient.
# Patients taking Coumadin may receive aspirin.

ASPIRIN (ASA) - Revision history